I believe that many people have experienced problems with their teeth, more or less. Some are unlucky and lose their teeth. When teeth fall out and create gaps, many people lose their confidence. Some may not dare to smile again. Also, chewing food is an obstacle. They do not chew thoroughly, causing indigestion and difficulty swallowing. But those problems may disappear when a start-up company…Toregem Biopharma (Toregem Biopharma) is a pharmaceutical company affiliated with Kyoto University, Japan. The world’s first successful tooth-growing medicine has been developed, which can be used to treat patients who have lost their permanent teeth.To have new teeth again
The drug trial was held at Kyoto University Hospital and was divided into two phases. Phase 1 involved 30 male patients aged 30 to 64 who had lost at least one molar. The trial began in May.September 2024 – August 2025, for a period of 11 months, administered intravenously.The first phase was successful, followed by the group of 2-7 years old with at least 4 missing teeth due to congenital dental defects. The teeth were found to have erupted and functioned without any significant side effects.
The reason why teeth in the human body do not grow again is because the body has a protein called Uterine Sensitization-Associated Gene-1 (ONE-1) It works by inhibiting tooth growth. The injected medication disables the protein and prevents it from reacting with another protein in the body that stimulates the signaling process. Bone Morphogenetic Protein (BMP) It is a protein that stimulates the formation of new bones. The experiment was successfully completed with the hope that it will not only treat patients with congenital tooth defects, but also treat the teeth of people of all ages.
Source: www.siamphone.com
